Usually, a cardiac tumor is benign in nature. A benign tumor has a good prognosis, but thrombi, vegetations and some tumors is embolization the main risk.

Primary benigne cardiac tumor

Tumor Description Location Size
Myxoma Most common primary cardiac tumor (50-75%). 90% atrial (LA 75%), 7% ventricular. 1-15cm (usually 5-6cm).
Fibroma Second most common primary cardiac tumor. Almost always ventricular (septal or apical). ± 10cm.
Papillair fibroelastoma Most common valve tumor. Whole heart, usually aortic valve (35%). ± 1cm.
Lipoma Usually, on the basis of the endocardium. Whole heart including valves and pericardium. Up to ± 10 cm.
Rhabdomyoma Most common benign cardiac tumor in children. Mostly ventricular, no valve involvement. 1mm-9cm.
Hemangioma Blood tumor, proliferation of endothelial cells. Whole heart  
Lambl's excrescences Valvular piece of string Ventricular side aortic valve. ± 1cm
Cysts Congenital unnatural body cavity lined with epithelium. Usually in the right atrium (right cardiofrenische corner).  
Thrombi Clots of blood by slow blood flow. Left atrial appendage with atrial fibrillation  
    akinetic myocardial infarction  
    prosthetic valves/infectious valves  
    atrial septal ASD / PFO  

Myxoom LA

Myxoma LA


Papillar fibroelastoma proximal septum


Primary malignant tumors are very rare. Most common malignant cardiac tumors are secondary tumors derived from primary diseases (see below). 3% of all patients with cancer receive cardiac metastases through the four “pathways”: direct infitration, haematogenically (through blood), lymphatic and vessels (IVC, pulmonary veins). Malignant tumors have a poor prognosis: In malignant tumors the main risk is the malignancy itself.

Primary malignant cardiac tumor

Tumor Description Location
Angiosarcoma Most common primary malignant cardiac tumor 90% Right atrium
Rhabdomyosarcoma Second most common primary malignant cardiac tumor, often in children than adults Whole heart
Mesothelioma Covering visceral and parietal pericardium, no growth in endocardial.  

Secundary maligne cardiac tumor

Location Tumor
Left atrium Myxoma
  Papillary fibroelastoma
Right atrium Myxoma
  Papillair fibroelastoma
Left ventricle Fibroma
  Papillair fibroelastoma
Right ventricle Fibroma
  Papillair fibroelastoma

The information above comes from Echocardiografie.nl. Last changed on: 5 September 2023.